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ARMGO™ is currently carrying out pharmaceutical research and development at the company’s laboratories in Tarrytown and Valhalla, NY. We are now seeking highly qualified and motivated individuals to join our team in the following positions. We offer competitive salaries, equity participation, superior medical and dental plans, a 401(k) retirement savings plan, and other benefits. |
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If you are interested in joining a well funded, privately held company and working on groundbreaking small-molecule therapeutics with the potential to restore function in people suffering from cardiovascular, muscle, and neurological disorders, please send your resume to hr@armgo.com. ARMGO™ Pharma, Inc. is an EQUAL OPPORTUNITY EMPLOYER. |
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Associate Director/ Director Assay Design & Implementation Group
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Associate Director/ Director Assay Design & Implementation Group
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Job Description: The Associate Director/Director is responsible for the design, implementation, troubleshooting and analysis of data from biochemical, membrane- and cell-based assays for small molecule RyR modulators. The Associate Director/Director enables and supports drug discovery efforts and will have responsibilities that include assay development & implementation, data analysis and interpretation, and preparation of reports. The Associate Director/Director will work closely with internal and external cross-functional stakeholders, external investigators, and corporate partners. The Associate Director/Director will represent ARMGO in meetings and will develop and deliver key presentations, both internally and externally.
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Knowledge
| • | Demonstrated track record in the design and implementation of pharmaceutical assay design and small molecule screening. |
| • | Demonstrated hands-on, bench-level leadership and clear scientific decision-making. |
| • | Demonstrated practical experience and success in technical problem-solving and troubleshooting. |
| • | Strong experience in the adaptation of low-throughput filter-based assays to multi-well, medium-throughput formats with a variety of readout technologies. Expertise in assay/automation quality control would be a plus. |
| • | Significant practical experience with membrane-based, cell-based and radioactive ligand filter binding assays. |
| • | Practical experience in data acquisition/analysis and automation of cell-based fluorescent assays, fluorescence microscopy and image analysis would be a plus. |
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Education: Ph.D. (Optimal would be someone with either a cardiovascular or musculoskeletal background.)
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Experience: 7+ years experience in industry (Pharma/Biotech) with significant practical experience in assay design and small molecule screening implementation. Excellent contacts and network in the assay design and screening community. Prior leadership experience in lead discovery and/or assay design & implementation in a pharmaceutical or biotech laboratory environment.
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Languages: English is required. French would be a plus.
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Research Associate II
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Research Associate II
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Job Description: The successful candidate will support discovery and innovation efforts by participation in protein biochemistry assays in research and development.
REQUIRED SKILLS:
| • | Strong core competency in protein and membrane biochemistry |
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| - | Recombinant bacterial expression and protein purification |
| - | Metabolic labeling using E coli expression systems |
| - | Membrane vesicle preparations of striated muscle |
| • | Biochemical/biophysical characterization of skeletal muscle |
| - | Binding assays: Membrane receptor-radioligand binding, immunoprecipitation, filter binding assays, ability to troubleshoot assays |
| - | Immunoblotting, QA/QC of skeletal muscle preparations |
| • | Skeletal muscle functional in vitro assays |
| - | Muscle force analysis of rodent EDL and soleus muscles using Aurora force analyzer |
DESIRED SKILLS:
• Design, construction and propagation of plasmid expression constructs
• Practical experience with qRT-PCR
• Effective oral and written communication, self-management, organization and task planning.
• Demonstrated skills in experimental planning, data analysis and presentation of results
Education: Bachelors or Masters Degree in muscle protein biochemistry in addition to a minimum of 5 years industry experience .
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